Banish 1 card on the field, and if it was a FIRE or DARK Monster Card, inflict damage to your opponent equal to its original Level x 200
Without dipping into another color we can run The Chain Veil, which can ramp things a little faster along with Contagion Clasp and Contagion Engine, and blue gives us Clockspinning and Inexorable Tide
Well, YOU, fellow seafarer, might as well flip over the top card of your life and turn that supernova into a blocker
Its also very easy to protect your Humans with cards like Coppercoat Vanguard, or make them all bigger with a Goldnight Commander or Cathars Crusade
If you think Ob Nixilis is going to end up being banned, itd be worth it to pick up a playset of Falco Spara now (while it is super cheap)