You can just attack your opponent anyway, regardless of whatever your opponent has on their field
Now, from a gameplay and design standpoint, Wrenn and Six push red and green into graveyard-focused value play rather than pure aggression
GX anime.
Aerial Formation Ajani, Inspiring Leader Akroma's Will Akroma's Will Appa, the Vigilant Archetype of Imagination Bahamut, Warden of Light Bane's Invoker Basri, Devoted Paladin Bleeding Effect Concerted Effort Cosmic Spider-Man Crown of Ascension Elspeth, Storm Slayer Elspeth, Undaunted Hero Flying Crane Technique Frostwind Invoker Gempalm Sorcerer Ghost-Lit Drifter Goblin Balloon Brigade Gustrider Exuberant Harbin, Vanguard Aviator Invert the Skies Iron Man, Armored Avenger Kinsbaile Balloonist Levitation Magnetic Flux Moonshae Pixie Moonshae Pixie Moonshaker Cavalry Nephalia Moondrakes New New York Phantasmal Form Rishei, Getaway Accomplice Scions of the Ur-Spider Seascape Aerialist Skyshaper Storm, Windrider Stormcaller's Boon Striding Shotcaller Ten Wizards Mountain The Wind Crystal Thunderhawk Gunship Triceraton Commander Victory's Herald Voyager Drake Vulture, Scheming Scavenger Web Wind Sail Windborne Charge Winged Sliver
This exiling ability is where Urza's Sylex shines