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Thus, determining GFR based on creatinine levels requires that doctors approximate the rate of creatinine generation, which may not take all variables into account (Shlipak, Mattes 2013)

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The designation bacteriostatic refers to the benzyl alcohol preservatives mechanism of action , benzyl alcohol at 0.9% w/v inhibits bacterial cell membrane integrity and disrupts metabolic function in a broad spectrum of Gram-positive and Gram-negative organisms, preventing microbial proliferation in reconstituted solutions without producing the bactericidal activity that would require higher antimicrobial concentrations