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WH, MC, and RH reviewed the literatures
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Quantitative Sensory Testing (QST) This helps to assess damage to the nerve endings involved in sensing temperature and vibrations, QST uses computer testing to measure how the nerves in question react to these stimuli
The development of individualized biomarkers (e.g., GABA/Glu ratios via MRI) and precision therapies (e.g., gene editing, stem cell-based interventions) could refine diagnostic and treatment strategies
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