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As well as stimulating insulin release, GLP-1R agonists promote satiety and reduce food intake, leading to weight loss
Association between Use of Sodium-Glucose Cotransporter 2 Inhibitors, Glucagon-like Peptide 1 Agonists, and Dipeptidyl Peptidase 4 Inhibitors with All-Cause Mortality in Patients with Type 2 Diabetes
Weaknesses The lack of required baseline lab work is concerning from a medical safety perspective
In the phase 2 dose-finding trial involving 706 participants, nausea rates varied dramatically by dose
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