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Direct Stimulation of GLP-1 Receptors in the Brain: GLP-1 receptors are found in various areas of the brain, particularly those involved in appetite control and the sensation of nausea
It mimics the endogenous hormone amylin, which is co-secreted with insulin from pancreatic beta cells
Note: Excessive consumption may have a laxative effect
Additionally, monoclonal antibodies targeting substances like fentanyl are being developed to block their effects before they reach the brain, potentially reducing overdose risks
Arans C, Edvardsson CE, Shevchouk OT, Zhang Q, Witley S, Blid Skldheden S, et al
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