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The landmark IDEA trial published in JAMA found that overweight and obese adults with knee osteoarthritis who lost just 10% of their body weight experienced significant reductions in pain and improvements in physical function
Peptides are not thyroid medications, but metabolic shifts may alter symptoms or lab values
Results depend on long-term habits and metabolic health
Degraded peptides may produce inconsistent or misleading results
Retatrutide activates the same receptors regardless of body size
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