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435 HSPs and inflammasome regulation in autoimmune diseases Inflammasomes are multiprotein complexes that play a central role in innate immunity by regulating the production of pro-inflammatory cytokines, such as interleukin-1 (IL-1) and IL-18
2.6 Microbial bioinformatics analysis Microbial bioinformatics analysis was performed as previously described ( 2.7 Preparation of serum samples for mass spectrometry analysis Serum samples were thawed on ice, and 100 L of each sample was mixed with 300 L of precooled methanol and acetonitrile (2:1, v/v)
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