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Acknowledgements We would like to thank the families of individuals with autism for the thoughtful donation of post-mortem tissues to the Autism Tissue Program at the Harvard Brain Tissue Resource Center, Belmont, MA,USA, and the NICHD Brain and Tissue Bank for Developmental Disorders at the University of Maryland, Baltimore, MD, USA

Furthermore, in patients with obesity, the fT3 to fT4 ratio is positively associated with BMI and waist circumference [61]

Scientists have discovered that glutathione can affect skin tone by inhibiting tyrosinase, the enzyme responsible for the first step in melanin synthesis (research review)

Breast-feeding women

For very sensitive patients, dosing can often be given very infrequently depending on the agent selected