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57 The most acute nutrient deficiency, Wernicke encephalopathy (WE), has been reported in a range of surgical procedures including: Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), biliopancreatic diversion with or without duodenal switch (BPD-DS), gastric banding, gastrojejunostomy, and intragastric ballooning
Replacement of Lys105 by uncharged residues in K105A/Y resulted in a 6597% decrease of the k cat app values for GSSCys and GSH (Fig
D.FaddoulF
PloS One 2015;10(3):e0118897
Conclusion While vitamin B12 injections are effective and generally safe, rare but serious adverse effects such as hypersensitivity and anaphylactic reactions can occur, particularly with parenteral administration
