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Wegovy, whilst more effective (average 10-15% weight loss in clinical trials), is reserved for specific circumstances and is only available through NHS specialist Tier 3 weight management services for people meeting specific criteria under TA875, with treatment limited to a maximum of 2 years
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GLP-1 receptors are located in the GI tract and brain
Overall, these data suggest that early acute inflammation is required for the correct recruitment of OPCs to the lesion site, but that chronic inflammation may impede remyelination (Figure 2)
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