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Nanoparticles were designed with a 2,2-(propane-2,2-diylbis(sulfanediyl)) bis(ethan-1-ol) linker that could be oxidized by ROS, decompose into oligomeric units, and release the ruthenium catalyst
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These include the catabolism of tyrosine, the synthesis of epinephrine from tyrosine (critical enzyme is dopamine -hydroxylase), the synthesis of carnitine, peptide hormone amidation, and the synthesis of bile acids
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