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These multifunctional conjugates were produced by ester chains that lyse when exposed to the mildly acid microenvironment of the arthritic synovial membrane

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Comparison With GLP-1 Receptor Agonists Studies have compared sitagliptin with GLP-1 receptor agonists in drug nave subjects with type 2 diabetes [exenatide, (110)] or as add on to other therapy for exenatide (111), semaglutide (112), albiglutide (113), and dulaglutide (114)

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