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MB272 targets T, B and dendritic cells to inhibit or blunt activation and suppress an inflammatory immune response
Chronic stress and inflammatory stimuli promote microglial activation, leading to sustained release of pro-inflammatory cytokines, reactive oxygen and nitrogen species, and excitotoxic mediators that disrupt synaptic function and neuronal integrity ( Neuroinflammation also interacts bidirectionally with dysregulation of the hypothalamicpituitaryadrenal (HPA) axis
Biol Psychiat
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