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They often evaluate whether a medication like Ozempic is medically necessary and fits within their formulary guidelines for weight management

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As efficacy benchmarks rise, the real differentiator may not be who builds the most complex molecule but who can execute across that complexity (trial design, patient stratification, safety signaling, real-world validation)

The main agents currently approved by the EMA and/or FDA include exenatide (2005/2005), liraglutide (2009/2010), lixisenatide (2013/2016), dulaglutide (2014/2014), semaglutide (2017/2017

doi: 10.4330/wjc.v2.i4.71