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It appears in human plasma at approximately 200 ng/ml in young subjects, with a drop of more than 60 % between ages 20 and 60, an observation that motivated forty years of research on its role in tissue repair, wound healing, hair growth and cutaneous longevity

It is frequently associated with metabolic signalling, appetite-regulation pathways, glucose-response models, energy expenditure, and weight-management

Its always a good idea to turn to a health-care provider if youre worried or have any questions

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