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Gozes group has found that ADNP mutations affect MT dynamics and inhibit its interactions with Tau [348, 349], producing a tauopathy-like phenotype manifested in increased GSK-3 activity, Tau hyper-phosphorylation, and cognitive deficiency [293]
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Healthy volunteers gave written informed consent and were compensated with $10 in cash
Tissues can convert ALA into EPA and DHA, but because the corresponding conversions are only 1 to 10% and 0.5-5% in human tissues, this conversion process is inefficient in humans (38)
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