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Bersuker K, Hendricks J, Li Z, Magtanong L, Ford B, Tang PH, et al
Mehta et al., 2020) that can cause acute respiratory distress syndrome, lung injury, respiratory insufficiency, endothelial cell dysfunction, thrombosis, cardiovascular disease and end-organ damage (Klok et al., 2020
Pojer, K
What the Evidence Does NOT Show Because the marketing around these compounds is expansive, it is worth stating explicitly what the published record does not establish: It does not show that cagrilintide is superior, equal, or inferior to tirzepatide no head-to-head trial exists, so any ranking is cross-trial inference
That intermediate position is exactly what makes a shuttle role plausible and also exactly what makes the compound behave differently in defined medium, in serum-containing medium and in a tissue matrix
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