Proposed definitions of typical lesions in hidradenitis suppurativa
Contact your GP or healthcare provider if you experience: Dark amber or brown urine persisting despite increased fluid intake, which may indicate severe dehydration or, rarely, liver dysfunction Urine colour changes accompanied by symptoms such as persistent vomiting, inability to tolerate oral fluids, severe diarrhoea, or abdominal pain Signs of dehydration : Dizziness, lightheadedness, dry mouth, passing urine less often than usual, dark or strong-smelling urine, or rapid heartbeat Red, pink, or cola-coloured urine : May indicate haematuria (blood in urine), requiring investigation for urinary tract pathology Cloudy or foul-smelling urine with dysuria : Suggests possible urinary tract infection Pale or clay-coloured stools with dark urine and jaundice : Rare but serious indicators of biliary obstruction or hepatic dysfunction For urgent advice : Contact NHS 111 if you cannot reach your GP and need help quickly
Ethics declarations Competing interests D.J.D
Always consult a knowledgeable practitioner to personalize your protocol
This study builds on Ro's strong foundation of clinical research, including eight abstracts that the company presented at ObesityWeek 2025 in November, spanning topics from the use of AI to improve the patient experience, such as an evaluation of Ro's LLM-enabled adverse event reporting tool, to outcomes among patients treated with GLP-1s, such as those with osteoarthritis
