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From these I have hypothesised additional forward actions that may likely see open label maintenance trials as hinted at in earnings call transcripts as well as commercialisation of VK2735 in 2029 and advancement of the DACRA pipeline
The most significant published evidence to date comes from a phase 2 randomised controlled trial (Jastreboff et al., New England Journal of Medicine , 2023), which demonstrated substantial dose-dependent weight loss in adults with obesity over 24 weeks, with continued weight reduction observed at 48 weeks
Whether youre using Zepbound or Mounjaro , youll start on the lowest dose
Weight loss isnt perfectly linear (because bodies arent spreadsheets), and having medical guidance makes adjustments feel far less frustrating
Chini CCS, et al
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