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Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N
Chronic kidney disease and risk management: Standards of care in diabetes-2024
The September 2025 wave of 50+ warning letters signaled escalating enforcement
The number of receptors per cell was calculated based on radioligand binding B max (maximum specific binding) values and the experimentally determined number of cells/mg of cell membrane protein
Chen C, Yang K, He D, Yang B, Tao L, Chen J, et al
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