glp-1 gip medication long term effects

glp-1 gip medication long term effects Genetics: How Genes Affect Appetite, Semaglutide, and Tirzepatide Response GLP-1 Drugs and the Physiology

Name: glp-1 gip medication long term effects Genetics: How Genes Affect Appetite, Semaglutide, and Tirzepatide Response GLP-1 Drugs and the Physiology
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Description

At high doses (over 3 g), nausea, stomach cramps, diarrhea, and a "fishy body odor" (trimethylamine accumulation) can occur

Inherited Defects in Folate Metabolizing Enzymes Pathogenic variants in the methylene THF reductase gene (MTHFR) are associated with a disorder that was originally referred to as hyperhomocysteinemia

Genome Medicine, 4(8), 67

Across both trials, the reported safety profile was described as consistent with prior experience for the compound class, with gastrointestinal adverse events predominating