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It targets different brain regions and hormonal systems, which is why its generating excitement both on its own and as part of the CagriSema combination
Diabetes 2014
Along with this there was a fairly pronounced reduction of the C-reactive protein inflammatory marker 39% vs 3% reduced, for semaglutide vs placebo, respectively
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The conjugate was able to penetrate the CNS without inducing toxicity in vivo and demonstrated inhibition of A aggregation and H 2 O 2 scavenging activity in in vitro conditions (Wang et al., 2016)
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