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Modern pharmacologic approaches allow the relative contribution of each receptor to be quantitatively tuned, mitigating adverse effects while preserving efficacy ( 5.3 Central neuropeptides and the behavioral dimension of feeding Beyond gut-derived peptides, centrally expressed neuropeptides exert a profound influence over feeding behavior while simultaneously modulating stress, arousal, and reward pathways
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Neuroscientist 14 , 182194 (2008)
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