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Elevated glutamate levels in the basal ganglia, an area of the brain devoted to motor control, motivation, and decision making, was found to be associated with depressed patients who also have systemic inflammation (Neuroscience Online)

Ongoing Monitoring Regular virtual check-ins ensure progress, safety, and motivation

The SELECT trial demonstrated that semaglutide 2.4 mg reduced major adverse cardiovascular events (heart attack, stroke, and cardiovascular death) by 20% in adults with overweight or obesity and established heart disease (Lincoff et al., SELECT trial, New England Journal of Medicine , 2023)

Patients lose weightbut not in the way they expected

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