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The efficacy of liraglutide on weight management was subsequently surpassed by semaglutide, which, when administered weekly at a dose of 2.4 mg in obese patients without diabetes, resulted in a weight reduction of 12.4% compared to placebo in the STEP 1 study [46], and a reduction of 9.4% compared to liraglutide 3.0 mg in the STEP-8 study [47]
From semaglutide at any dose, your GLP-1 receptors are pre-adapted
People tracking their progress with tools like the semaglutide dosage calculator should know that proper dosing correlates with these metabolic improvements
Beyond that, it works on several complementary pathways that together build a compelling case for its role in weight management
Mathes et al., 2016)
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