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A blood test is an indication for how much the brain might have access to B12, but if for instance the blood-brain barrier does not absorb enough B12, the brain will have too little B12, while the blood test is normal

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Front Public Health 2:112

The comparison the table is built to make is not "which route is best." It is "which route fits the gap between your skin goals and your budget." Topical creams have a defensible role in daily maintenance