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Owing to their distinct biochemical mechanisms that suppress lipid peroxidation and reduce ROS production, these compounds have been investigated in clinical studies to assess the therapeutic value of their antioxidant properties (Table 1)
Ferroptosis has been proposed as one mechanism of neuron injury in response to irradiation and has been observed in hippocampal neurons of irradiated mice [48]
313,314 The diet is rich in anti-inflammatory and free radical-scavenging nutrients, and has been shown to improve gut microbiome balance and promote cardiovascular and metabolic health, which can contribute to brain health
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