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They face chemical instability through hydrolysis and deamidation, and physical instability through aggregation and surface adsorption
Semaglutide is not recommended during pregnancy, and contraception should be discussed with the prescribing physician
Its potential is in a real biological effect involving tissue repair, control of inflammation, development of blood vessels, as well as in a general positive safety profile observed in animal studies and off-label use
Her blood pressure dropped to 90/58 mmHg
However, only baseline BMI was considered as confounding factor for the evaluation of beneficial impact of semaglutide on this cohort Table 2
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