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Severe GI Disorders: If you have a history of gastroparesis (paralysis of the stomach) or inflammatory bowel disease, the combined digestive side effects may be too severe
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This significant reduction in liver fat content with cotadutide is likely to be due to hepatic glucagon signalling and subsequent upregulation of fatty acid oxidation
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9 This was a 72-week double blind, randomized, placebo-controlled phase 3 trial comparing tirzepatide 5mg, 10mg, and 15mg to placebo
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