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Canagliflozin Canagliflozin (Invokana) was approved for use in people with T2D by the EMA and the FDA in 2013

Puniani et al., 2025)

Daily Pill vs Weekly Injection The injection - One weekly injection, any time of day, with or without food

There are criteria to meet before patients can be prescribed Orlistat, either on the NHS or privately: If you get Orlistat via a private prescription, a monthly dose will cost from around 58

These restrictions exist because oral semaglutide uses an absorption enhancer called SNAC to get through the stomach lining, and food interferes with that process

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