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We do not know how much of it is absorbed through the skin, but generally, barring a few chemicals such as hydroquinone, absorption from intact skin is minimal
This translates to approximately 58 pounds for a 240-pound individual, making it the largest weight reduction observed in any obesity drug trial at that time
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As of January 2025, the label now includes explicit warnings for severe pancreatitis, acute kidney injury, ileus, gallbladder disease, and pulmonary aspiration
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