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If AngII activation of the AT 1 receptor subtype results in facilitation of the NADPH oxidase complex and formation of free radicals, then blockade of the AT 1 receptor should serve a protective function
Arch Pharm Res 41(4):372383
Animal Model:NMRI-Hannover (male, 30 g, deep partial skin thickness burns induced by 5 s direct flame exposure covering 20% total body area) [2] Dosage:i.p.: 10 ng/kg, 10 g/kg
Zhao Z, Liu W
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