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In clinical trials, arginine has been used safely with minor side effects for up to three months

According to the researchers, Contrary to reports of increases in suicidal ideation with semaglutide, our analyses revealed a lower risk for both incidence and recurrence of suicidal ideation in patients prescribed semaglutide compared with non-GLP1R agonist anti-obesity and anti-diabetes medications. 20 If you look at the study a little bit deeper there was a decreased risk in [suicidal ideation] in women, men and along every racial group, said Catherine Varney, DO, obesity medicine director for UVA Health and an assistant professor of family medicine at the University of Virginia

References Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Bhatta L

Balance between on- and off-target effects of the dual GLP1/E agonist, and the concurrence of desensitization at very high doses, might contribute to this phenomenon

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