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All mice that were subjected to an HFD had a higher fat mass compared to the LD control group at the start of the study
This process consumes cellular methyl donors and, critically, prevents nicotinamide from being recycled into NAD+
However, that energy effect is only true to the extent that they were B12 deficient in the first place
Proper storage and handling will help maintain methylcobalamins effectiveness throughout your treatment course
Clin Biochem
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