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Chronic hypersecretion of GH into the circulation, usually from a GH-secreting pituitary adenoma, is classically associated with acromegaly, a debilitating disease characterized by excessive skeletal growth, soft tissue enlargement, insulin resistance, and cardiovascular and gastrointestinal morbidities
L-carnitine supplements reduce markers of muscle damage (creatine kinase and myoglobin)
NAD+ therapy restores the cellular fuel supply that powers DNA repair (via PARP enzymes), sirtuin activation (the longevity gene pathway), and mitochondrial energy production
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Heliyon 8 (11), e11411
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