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This depends very much on what condition you are treating and its severity

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Hughes Syndrome is a major cause of: DVT

The protective role of nutritional antioxidants - including glutathione precursors and direct glutathione supplementation - against impaired redox homeostasis in thyroid pathologies has been highlighted in a comprehensive review in PMC (2023), which confirmed that antioxidant interventions represent a promising adjunct strategy in the management of various thyroid conditions

Using knock-out mice it has been clearly demonstrated that Mn-SOD (SOD2) is essential for the maintenance of normal mitochondrial function in highly oxidative tissues such as the brain and heart as well as the liver