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Elevated levels of pro-inflammatory cytokines, such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-), generate massive amounts of reactive oxygen species (ROS)
Gallwitz B, Guzman J, Dotta F, et al
The British Menopause Society has highlighted this concern, noting that while there is currently no robust data showing that GLP-1 receptor agonists definitively affect oral progestogen dosing requirements, bleeding patterns, or endometrial risk, the theoretical concern is valid and warrants monitoring
Synapse alterations in the hippocampal-entorhinal formation in Alzheimer's disease with and without Lewy body disease Brain Res 1994
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