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(ii) BSO sensitized BTC cells to cisplatin through GSH depletion and downregulation of antiapoptotic proteins (Mcl-1, Bcl-2 and Bcl-xL)

Cells begin producing keratin and lipids as they move up to strengthen the skin and contribute to the protective barrier

Cyanocobalamin has been well researched and has proven to be very effective and well utilised in the body, in practice

Altered intestinal permeability (leaky gut) allows the passage of food antigens, toxins, bacteria, and microbial products, promoting inflammation and dysregulated immune responses, triggering autoimmunity through various mechanisms [188]

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