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Purpose-built for physicians Orthopedics Today Commentary Balance the benefits, risks of GLP-1 medications in orthopedic surgery Orthopedics Today Commentary The rapid increase in the use of glucagon-like peptide-1 receptor agonists for weight loss, diabetes management and cardiovascular health has significant implications for orthopedic surgery
This is of potential clinical relevance, as further defining the commonalities and differences between GLP-1R agonists and bariatric surgery in terms of their central mechanism of action may not only help bridge the gap between the pharmacological and surgical treatments for obesity but may also provide a neural basis for their combined use when each individually fail [174, 175]
Balupillai A, Nagarajan RP, Ramasamy K, Govindasamy K, Muthusamy G
Sitagliptin, a dipeptidyl peptidase-4 inhibitor, decreases systolic blood pressure in Japanese hypertensive patients with type 2 diabetes
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