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In addition to JPH-203, other drugs currently in preclinical and clinical trials targeting LAT1 include IPA-131, QBS-10072S, TLX101-CDx, 124I-ACD-101, 211At-TLX-102, OKY-034, [18F] NKO-028 (Table 1)

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Moreover, the immunomodulating effect of the combination of selenomethionine and myoinositol in HT was confirmed by the fact that after treatment the level of the chemokine CXCL10, which is a potent chemoattractant for activated T-lymphocytes, also decreased, suggesting the possibility of reducing the risk of progression of euthyroidism to hypothyroidism (81)