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Patients should contact their healthcare provider if cold intolerance is accompanied by severe fatigue, hair thinning or loss, persistent constipation, cognitive impairment, or depression , as these may indicate thyroid dysfunction requiring laboratory assessment

Allow vials to reach room temperature before opening to reduce condensation uptake [10]

After 12 h treatment, 10 L of MTT solution (5 mg/mL in phosphate buffer solution) was added into the each well

Our bodies were designed to handle stress, detoxify chemicals and preserve cell function, but when the burden increases, those naturally built-in systems cant keep up with demand