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In addition, anchoring IL-2 and anti-CD137 on the surface of liposomes not only allows these immune agonists to rapidly accumulate in tumors, but also induces a large proliferation of CD8 + T cells and increases the intratumoral CD8/Treg ratio, thereby producing strong anti-tumor activity (144)
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A less significant reduction of VAS scoring was observed in the only report of non-diabetic group (MD, 0.71
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