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h , Relative abundance of cecal metabolites, including short-chain fatty acids (SCFA), branched-chain amino acids (BCAA), tricarboxylic acid intermediates (TCAi), and metabolites involved in creatine synthesis, quantified by nuclear magnetic resonance (NMR)
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Manufacturers and lactation experts recommend caution due to theoretical risks, unknown infant metabolic effects, and lack of safety data in vulnerable populations
Although these trials primarily enrolled individuals with relatively low DKD risk and were not designed to evaluate kidney outcomes specifically, exploratory analyses consistently indicated slower kidney disease progression across diverse eGFR and albuminuria levels [39-44]
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