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Description

9c, a synthetic1-(3-(aryl-4,5-dihydroisoxazol-5-yl)methyl)-4-trihalomethyl-1H-pyrimidin-2-one compound, could induce mitochondrial depolarization and activate the intrinsic pathway, leading to apoptosis in PC cells by increasing cleavage of caspase-9 and -3 (Schmauss et al., 1988)

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