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Animal Model and Ethics Statement Wistar rats from the breeding colony at the Universidade do Extremo Sul Catarinense (UNESC), Brazil, were housed four times per cage under controlled conditions of temperature (22 1 C), relative humidity (4555%) and light-dark cycle (12:12 p.m., light on at 6 a.m.)
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PMID: 17597598 Belosic Halle O, et al
injectable) and where it comes from (regulated drug vs
High doses may amplify the risk of adverse effects, including digestive and cardiovascular issues
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