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During this tapering window, intensify dietary structure, increase meal frequency to prevent large hunger spikes, and prioritize protein intakestudies confirm protein consumption amplifies satiety signals that partially compensate for GLP-1 withdrawal

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Both SUSTAIN-6 and LEADER showed a statistically significant decrease in MACE [53, 54]

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Christopher McGowan, MD, a gastroenterologist and obesity medicine specialist, told Medical News Today that: Losing weight at the expense of lean muscle can lead to future problems, including reduced basal metabolic rate, decreased strength, fitness, and tone, reduced bone density, and an increased risk of weight recurrence