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By binding to these receptors, GLP-1 enhances insulin secretion from pancreatic -cells and suppresses glucagon secretion in a glucose-dependent manner, slows gastric emptying, and regulates appetite by increasing satiety and promoting a sense of fullness through its action on the hypothalamus [27, 28, 31,32,33]
Lillys tirzepatide (Mounjaro and Zepbound) is similarly a modified and stabilised form of the related glucose-dependent insulinotropic polypeptide (GIP) hormone
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P = 0.007)
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