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These drugs bind to the GLP-1 receptor and: Lower blood sugar by increasing insulin and reducing glucagon Slow gastric emptying Reduce appetite and food cravings Support clinically significant weight loss in many people They are commonly prescribed for: Type 2 diabetes Obesity or overweight with weight-related health risks Trials suggest GLP-1 agonists can reduce body weight by around 5 to 18 per cent on average, often with improvements in blood pressure, cholesterol and other cardiometabolic markers
Human epidemiological data presents mixed results, though some studies indicate correlations between elevated IGF-1 levels and increased risk of certain cancers, particularly breast, prostate, and colorectal cancers
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Athletes subject to testing should consult the current rules of their anti-doping organization and qualified sports-medicine professionals
The common dogma you hear is everybody gains the weight back pretty quickly [after stopping a GLP-1], and most people gain back even more weight than when they started, and that can happen to some people, he said
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