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In a T cell-mediated chronic psoriasiform inflammation model, investigators observed the coexistence of pro-inflammatory macrophages expressing iNOS and alternatively activated macrophages expressing Arg1 in lesional tissues, suggesting that the partitioning of arginine metabolic pathways participates in regulating macrophage phenotypes and the intensity of inflammatory responses
doi:10.1016/S0167-7799(01)01813-3
Oswaldo Cruz , 90 , 235240
The MTT assay was performed according to the instructions, and absorbance was measured at 490 nm
Deficiency of liver kinase B1 (LKB1) may increase glucose and glutamine uptake and utilization in a HIF1-dependent way (Faubert et al., 2014)
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